Board Thread:False Info and Speculative Discussion/@comment-4772791-20160227093034/@comment-11533671-20160227222723

I think the reason why chimeras were used was because the experiments could only succeed with them for some scientific reason or another.

Also, it might be that the Dread Doctors wanted the Beast to be unaffected by the conventional weapons and hindrances that affect other werewolves. They weren't just recreating the Beast, they want it to be more deadly and almost impossible to stop.