Board Thread:Legitimate Canon Questions/@comment-25038237-20140614152013/@comment-4091815-20140614155926

It is, at this time, suspected that the Mexican Hunters were searching for Kate Argent when they questioned Derek and Peter about "La Loba."

The other prevailing theory is that "La Loba" referred to the remains of Talia Hale.

Both are logical conclusions based on what we know currently - neither is actually canon until it is explained on the show.