Clunie was born in Portland, Oregon, where she studied tap, jazz, violin, and ballet for which she studied and apprenticed at The Academy of Professional Ballet.
At 19 years old, she moved to Los Angeles, California to pursue an acting career.
Clunie’s Los Angeles stage debut earned her a Dramalogue Award for Best Actress in Dean Orion’s A Comedy of Eros performed at the Skylight Theatre. Her other stage highlights include The Mercy Street at Ford Theatre and the Off-Broadway production of her play, US.
She began to take small roles in films like Jason Goes to Hell: The Final Friday, Lost & Found, The Usual Suspects, Magic Mike, and A Sort of Homecoming.
In 1995, she gained a role on The Jeff Foxworthy Show which lead to other guest spots on shows like ER, Boy Meets World, The Tony Danza Show, House M.D., Without a Trace, NCIS, CSI: Crime Scene Investigation, The Mentalist, Diagnosis: Murder, Bones, and In Plain Sight.
Her most notable roles to date are the lead role of Melanie Marcus in Queer as Folk where she met future Teen Wolf director Russell Mulcahy and the recurring role of Ellen Beals on the ABC Family show, Make It or Break It.