Vizzini grew up in Brooklyn where he attended Stuyvesant High School in Manhattan.
He published his first essay to the New York Press and became a freelance writer for the paper while attending school. These columns would become the core for his first book, "Teen Angst? Naaah...." which is a memoir of his teenage years.
In 2004, he wrote his first novel "Be More Chill" which received mixed reviews upon its release. He continued to write novels based on young adult fiction such as "The Other Normals", "House of Secrets", "House of Secrets: Battle of the Beasts", and "It's Kind of a Funny Story" which was made into a film in 2010 and named #56 of the "100 Best-Ever Teen Novels" by NPR.
Suffering from mental health issues, Vizzini spoke at schools and libraries on the subject to raise awareness on the matter. He contributed to a documentary, At-Risk Summer to discuss his problems along with others to continue raise awareness.
Collaboration with Nick AntoscaEdit
In 2013, they were story editors on ABC's drama series Last Resort where they also wrote the episode "Nuke It Out." They also worked as executive story editors for Alfonso Cuarón's show Believe.
He was found dead in his native Brooklyn, New York after an apparent suicide from a fall from his parent's home.
The pilot episode of Believe was dedicated to his memory.