Antosca was born in New Orleans, Louisiana and graduated from Yale University in 2005 before moving to Los Angeles, California.
Following college, he published his first novel, "Fires", in 2006 while writing articles for various literary and online magazines like The New York Sun, n+1, Film Threat, Exotic Gothic, and The Daily Beast. It would soon be followed by books like "Midnight Picnic" (2009), "The Hangman's Ritual", "The Obese", and "The Girlfriend Game" (2013) which is a collection of short stories.
Antosca also stretched his skills into the entertainment industry where he helped produce and write episodes for shows like The Player, Hannibal, and Channel Zero which he created and lasted from 2016 to 2018.
His screenplays found their way to fruition such as The Norseman, The Forest, The Cottage, the short Soon You Will Be Gone and Possibly Eaten, and The Girlfriend Game based off his own book.